Sir Charles Gairdner Hospital has opened ward G 71, which may deal with as much as 26 COVID-19 sufferers.
When Omicron hospitalisations are at their peak, the hospital has plans to open different wards.
"Our aim is to get sufferers higher shortly and maintain them out of ICU if in any respect doable," mentioned Sir Charles Gairdner's Professor Fraser Brims.
The COVID-19 ward will predominantly use high-flow oxygen and CPAP machines to assist sufferers with their respiratory.
Medicine used to deal with the virus have additionally come a great distance for the reason that pandemic started greater than two years in the past.
"We have the most recent antivirals and another actually vital medicines that may now make fairly a dramatic distinction for sufferers with Covid," mentioned Professor Brims.
The hospital's emergency division additionally seems vastly completely different within the COVID-19 period.
Sufferers are greeted outdoors by a nurse, the place they reply questions and have their temperature taken.
It used a 'visitors mild system.
No COVID-19 signs means a inexperienced mild to proceed as regular.
Sufferers with Covid-like signs head to a separate 'orange' part to take a speedy take a look at.
Confirmed COVID-19 instances enter the 'crimson' zone which has HEPA filters and isolation rooms.
These rooms have detrimental strain so when the door opens contaminated air does not move out.
In orange and crimson sections, workers put on full PPE - together with N95 masks.
Emergency doctor Dr Lindsay Showers mentioned he hopes folks will likely be affected person with the brand new processes.
"You'll require some form of testing and that does take time. There's nothing we will do about that and it is completely important," she mentioned.
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"We do really feel prepared. We really feel prepared to present the perfect care we will."